🔗 Share this article Depression Drug Adverse Reactions Like Body Weight, Blood Pressure Changes Range Depending on Medication Latest study delivers strong findings of the extensive array of antidepressant medication adverse reactions. A comprehensive recent investigation determined that the side effects of antidepressants vary considerably by drug. Some pharmaceuticals led to reduced body weight, while others resulted in weight gain. Pulse rate and BP additionally differed markedly between medications. Individuals experiencing persistent, serious, or concerning adverse reactions should discuss with a healthcare professional. Recent investigations has revealed that depression drug side effects may be more varied than once assumed. This comprehensive study, released on October 21st, analyzed the influence of depression treatments on over 58,000 subjects within the first 60 days of commencing medication. These scientists examined 151 investigations of 30 pharmaceuticals commonly prescribed to manage depression. While not all individuals experiences side effects, certain of the most common noted in the study were fluctuations in body weight, blood pressure, and metabolic markers. The study revealed notable variations among antidepressant drugs. For instance, an two-month treatment period of agomelatine was connected with an average decrease in mass of about 2.4 kilograms (approximately 5.3 pounds), while another drug patients added close to 2 kg in the identical duration. Additionally, notable changes in cardiovascular activity: one antidepressant often would slow pulse rate, whereas another medication raised it, creating a difference of around 21 BPM across the two drugs. Arterial pressure varied also, with an 11 millimeters of mercury disparity noted between nortriptyline and doxepin. Antidepressant Adverse Reactions Include a Broad Spectrum Healthcare specialists observed that the research's conclusions are not considered novel or surprising to psychiatrists. "It has long been understood that different antidepressant medications range in their influences on weight, BP, and other metabolic measures," a specialist explained. "Nevertheless, what is remarkable about this research is the thorough, relative quantification of these differences among a broad array of bodily measurements using data from in excess of 58,000 participants," the specialist commented. This research offers robust proof of the extent of side effects, certain of which are more frequent than others. Typical antidepressant medication unwanted effects may include: digestive issues (nausea, bowel issues, irregularity) sexual problems (decreased libido, anorgasmia) weight changes (gain or decrease, based on the drug) rest issues (inability to sleep or drowsiness) oral dehydration, moisture, head pain At the same time, rarer but therapeutically relevant side effects may comprise: rises in arterial pressure or pulse rate (notably with SNRIs and some tricyclics) low sodium (particularly in elderly individuals, with SSRIs and serotonin-norepinephrine reuptake inhibitors) elevated hepatic parameters QTc lengthening (risk of abnormal heart rhythm, notably with one medication and certain tricyclic antidepressants) reduced emotions or lack of interest "A key factor to note here is that there are multiple different categories of antidepressant medications, which lead to the distinct unwanted medication reactions," another professional stated. "Furthermore, depression treatments can impact each person variably, and adverse effects can range depending on the particular medication, dosage, and individual elements such as body chemistry or co-occurring conditions." Although several side effects, including changes in sleep, hunger, or stamina, are reasonably common and commonly enhance as time passes, other effects may be less typical or more persistent. Speak with Your Physician About Serious Adverse Reactions Antidepressant medication side effects may vary in severity, which could require a adjustment in your treatment. "An adjustment in antidepressant medication may be appropriate if the individual encounters continuing or unbearable adverse reactions that fail to enhance with duration or management strategies," one expert commented. "Moreover, if there is an development of recent health problems that may be aggravated by the present treatment, such as hypertension, irregular heartbeat, or considerable increased body weight." Patients may furthermore contemplate speaking with your physician concerning any absence of meaningful improvement in low mood or worry signs subsequent to an sufficient evaluation duration. The adequate testing period is typically 4–8 weeks duration at a therapeutic dose. Individual choice is furthermore crucial. Certain individuals may choose to prevent particular unwanted effects, including sexual dysfunction or {weight gain|increased body weight|mass addition